The importance of recognizing paraneoplastic symptoms: a case report of Neuroendocrine Small Cell Carcinoma of the Endometrium presenting as Paraneoplastic Cushing’s Syndrome.

Keywords:

Corpus uteri, Carcinoma, Cushing’s syndrome, Paraneoplastic syndrome, Small cell carcinoma, euroendocrine 


Published online: Oct 25 2017

A Doukhopelnikoff1, G Debrock2, T Steelandt3, ETM De Jonge4

KULeuven, Faculty of Medicine, Gasthuisberg, Herestraat 49, 3000 Leuven, Belgium
Department of Oncology, Ziekenhuis Oost-Limburg Campus St Jan, Schiepse Bos 6, 3600 Genk, Belgium
Department of Pathology, Ziekenhuis Oost-Limburg Campus St Jan, Schiepse Bos 6, 3600 Genk, Belgium
Department of Obstetrics & Gynaecology, Ziekenhuis Oost-Limburg Campus St Jan, Schiepse Bos 6, 3600 Genk, Belgium. 

Abstract

This is the second well documented case of paraneoplastic Cushing’s syndrome arising from a small cell carcinoma of the endometrium described in English literature. This tumour has an aggressive biological behaviour and early detection provides the only opportunity for long-term survival. In that regard recognition of associated paraneo- plastic features might be helpful.